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GNA11 rabbit pAb
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ES9703
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: GNA11 rabbit pAb
反应性: Human;Rat;Mouse
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from part region of human protein
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 39kD
基因ID: 2767
蛋白序列: P29992
细胞定位: Cell membrane ; Lipid-anchor . Cytoplasm . In testicular cells, expressed exclusively in the cytoplasm.
研究背景: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013],
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