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PAK6 rabbit pAb
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ES8980
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PAK6 rabbit pAb
反应性: Human;Mouse
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human protein . at AA range: 100-180
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 74kD
基因ID: 56924
蛋白序列: Q9NQU5
细胞定位: Cytoplasm. Nucleus. Cotranslocates into nucleus with AR in response to androgen induction.
研究背景: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
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