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MYBPC3 rabbit pAb
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ES8931
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: MYBPC3 rabbit pAb
反应性: Human;Mouse;Rat
别名: Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: Synthesized peptide derived from human MYBPC3 Polyclonal
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 140kD
基因ID: 4607
蛋白序列: Q14896
细胞定位: cytosol,striated muscle myosin thick filament,C zone,sarcomere,A band,
研究背景: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],
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