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CCR5 rabbit pAb
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ES8888
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CCR5 rabbit pAb
反应性: Human;Mouse;Rat
别名: C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA 1:10000-20000
免疫原: Synthesized peptide derived from human CCR5 Polyclonal
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 40kD
基因ID: 1234
蛋白序列: P51681
细胞定位: Cell membrane ; Multi-pass membrane protein .
研究背景: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok
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