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IGF1R (Phospho-Tyr1161) Rabbit pAb
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ES8878
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: IGF1R (Phospho-Tyr1161) Rabbit pAb
反应性: Human;Mouse;Rat
别名: Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA 1:10000-20000
免疫原: Synthesized phospho derived from human IGF1R (Phospho-Tyr1161)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: pro: 155kD, recetor beta: 95kD
基因ID: 3480
蛋白序列: P08069
细胞定位: Cell membrane ; Single-pass type I membrane protein .
研究背景: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
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