Synthesized peptide derived from human GCK/GLK. at AA range: 221-270
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
100kD
基因ID:
5871/8491
蛋白序列:
Q12851/Q8IVH8
细胞定位:
Cytoplasm . Basolateral cell membrane ; Peripheral membrane protein . Golgi apparatus membrane ; Peripheral membrane protein .
研究背景:
mitogen-activated protein kinase kinase kinase kinase 2(MAP4K2) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],