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FIG4 rabbit pAb
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ES8837
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: FIG4 rabbit pAb
反应性: Human;Mouse
别名: Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA 1:10000-20000
免疫原: Synthesized peptide derived from human FIG4. at AA range: 341-390
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 110kD
基因ID: 9896
蛋白序列: Q92562
细胞定位: Endosome membrane . Localization requires VAC14 and PIKFYVE. .
研究背景: The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008],
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