Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
宿主:
Rabbit
稀释比:
WB 1:500-2000, ELISA 1:10000-20000
免疫原:
Synthesized peptide derived from human Parafibromin. at AA range: 51-100
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
60kD
基因ID:
79577
蛋白序列:
Q6P1J9
细胞定位:
Nucleus .
研究背景:
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],