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E2F-1 (Acetyl-K117) rabbit pAb
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ES8820
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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产品名称: E2F-1 (Acetyl-K117) rabbit pAb
反应性: Human;Mouse;Rat
别名: Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
宿主: Rabbit
稀释比: wb dilution 1:2000
免疫原: Synthesized Acetyl peptide derived from human E2F-1. at AA range: K117
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 60kD
基因ID: 1869
蛋白序列: Q01094
细胞定位: Nucleus .
研究背景: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
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