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TGFβ2 rabbit pAb
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ES8706
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: TGFβ2 rabbit pAb
反应性: Human;Mouse;Rat
别名: Transforming growth factor beta-2 (TGF-beta-2;BSC-1 cell growth inhibitor;Cetermin;Glioblastoma-derived T-cell suppressor factor;G-TSF;Polyergin)
宿主: Rabbit
稀释比: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
免疫原: The antiserum was produced against synthesized peptide derived from human TGF beta2. AA range:361-410
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 47+12kD
基因ID: 7042
蛋白序列: P61812
细胞定位: [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix .; [Transforming growth factor beta-2]: Secreted .
研究背景: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the an
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