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EGF rabbit pAb
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ES8651
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: EGF rabbit pAb
反应性: Human;Rat;Mouse;
别名: Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
宿主: Rabbit
稀释比: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
免疫原: Synthetic peptide from human protein at AA range: 1000-1060
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 130kD
基因ID: 1950
蛋白序列: P01133
细胞定位: Membrane; Single-pass type I membrane protein.
研究背景: This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],
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