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DAAM1 rabbit pAb
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ES8614
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: DAAM1 rabbit pAb
反应性: Human;Mouse
别名: Disheveled-associated activator of morphogenesis 1
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA 1:10000-20000
免疫原: Synthetic peptide from human protein at AA range: 400-500
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 123kD
基因ID: 23002
蛋白序列: Q9Y4D1
细胞定位: Cytoplasm . Cytoplasm, cytoskeleton, cilium basal body . Perinuclear.
研究背景: Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct
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