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WISP-3 rabbit pAb
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ES8588
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: WISP-3 rabbit pAb
反应性: Human;Rat;Mouse;
别名: WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6)
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA 1:10000-20000
免疫原: The antiserum was produced against synthesized peptide derived from the N-terminal region of human WISP3. AA range:1-50
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 55kD
基因ID: 8838
蛋白序列: O95389
细胞定位: Secreted . Mitochondrion . Associated with membranes. .
研究背景: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple
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