COL17A1 rabbit pAb-ELK科鹿生物-ELISA试剂盒、抗体、蛋白、分子

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COL17A1 rabbit pAb

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ES8550

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

产品名称:	COL17A1 rabbit pAb
反应性:	Human;Rat;Mouse;
别名:	COL17A1 BP180 BPAG2
宿主:	Rabbit
稀释比:	WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
免疫原:	The antiserum was produced against synthesized peptide derived from the Internal region of human COL17A1. AA range:481-530
储存条件:	-20°C/1 year
克隆性:	Polyclonal
抗体亚型:	IgG
浓度:	1 mg/ml
实测条带:	150kD
基因ID:	1308
蛋白序列:	Q9UMD9
细胞定位:	Cell junction, hemidesmosome. Membrane; Single-pass type II membrane protein. Localized along the plasma membrane of the hemidesmosome.; [120 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane. Exclusively localized to anchoring filaments. Localized to the epidermal side of split skin.; [97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane. Localized in the lamina lucida beneath the hemidesmosomes.
研究背景:	This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008],

Immunofluorescence analysis of A549. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
Western Blot analysis of 3T3, hepg2 cells using Antibody diluted at 500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:200

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