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MYOZ2 rabbit pAb
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ES8545
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: MYOZ2 rabbit pAb
反应性: Human;Mouse;Rat
别名: MYOZ2 C4orf5
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human MYOZ2. AA range:21-70
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 30kD
基因ID: 51778
蛋白序列: Q9NPC6
细胞定位: Cytoplasm, myofibril, sarcomere, Z line . Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle. .
研究背景: The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011],
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