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SPOP rabbit pAb
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ES8522
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: SPOP rabbit pAb
反应性: Human;Mouse;Rat
别名: Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human SPOP. AA range:41-90
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 42kD
基因ID: 8405
蛋白序列: O43791
细胞定位: Nucleus . Nucleus speckle .
研究背景: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
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