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Plasminogen receptor rabbit pAb
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ES8519
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Plasminogen receptor rabbit pAb
反应性: Human;Rat
别名: Plasminogen receptor (KT) (Plg-R(KT))
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 17kD
基因ID: 55848
蛋白序列: Q9HBL7
细胞定位: Cell membrane ; Multi-pass membrane protein . Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. .
研究背景: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
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