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ETBR rabbit pAb
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ES8504
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: ETBR rabbit pAb
反应性: Human;Rat;Mouse;
别名: Endothelin B receptor (ET-B;ET-BR;Endothelin receptor non-selective type)
宿主: Rabbit
稀释比: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
免疫原: Synthesized peptide derived from ETBR at AA range: 31-80
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 50kD
基因ID: 1910
蛋白序列: P24530
细胞定位: Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins. .
研究背景: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],
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