Endothelin B receptor (ET-B;ET-BR;Endothelin receptor non-selective type)
宿主:
Rabbit
稀释比:
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
免疫原:
Synthesized peptide derived from ETBR at AA range: 31-80
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
50kD
基因ID:
1910
蛋白序列:
P24530
细胞定位:
Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins. .
研究背景:
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],