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AMBRA1 rabbit pAb
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ES8480
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: AMBRA1 rabbit pAb
反应性: Human;Mouse
别名: autophagy/beclin-1 regulator 1
宿主: Rabbit
稀释比: WB 1:500-2000, ELISA 1:10000-20000
免疫原: Synthetic Peptide of AMBRA1
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 140kD
基因ID: 55626
蛋白序列: Q9C0C7
细胞定位: Endoplasmic reticulum . Cytoplasm, cytoskeleton . Cytoplasmic vesicle, autophagosome . Mitochondrion . Cytoplasm, cytosol . Nucleus . Cell junction, focal adhesion . Localizes to the cytoskeleton in absence of autophagy induction (PubMed:20921139). Upon autophagy induction, AMBRA1 relocalizes to the endoplasmic reticulum to enable autophagosome nucleation (PubMed:20921139). Partially localizes at mitochondria in normal conditions (PubMed:21358617). Localizes also to discrete punctae along the ciliary axoneme (By similarity). .
研究背景: function:Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.,similarity:Contains 3 WD repeats.,subunit:Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.,
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