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E2F-1 (Acetyl Lys120) rabbit pAb
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ES8446
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: E2F-1 (Acetyl Lys120) rabbit pAb
反应性: Human;Mouse;Rat
别名: E2F1 RBBP3
宿主: Rabbit
稀释比: WB: 1:500-10000 ELISA: 1:10000
免疫原: Synthesized acetyl-peptide from human protein at AA range: 100-170
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 60kD
基因ID: 1869
蛋白序列: Q01094
细胞定位: Nucleus .
研究背景: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
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