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PI 3-Kinase C2γ rabbit pAb
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ES8365
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: PI 3-Kinase C2γ rabbit pAb
反应性: Human;Rat;Mouse;
别名: PIK3C2G; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ.
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 160kD
基因ID: 5288
蛋白序列: O75747
细胞定位: Membrane ; Peripheral membrane protein .
研究背景: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
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