Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原:
Synthesized peptide derived from Otubain-1 . at AA range: 20-100
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
31kD
基因ID:
55611
蛋白序列:
Q96FW1
细胞定位:
Cytoplasm .
研究背景:
OTU deubiquitinase, ubiquitin aldehyde binding 1(OTUB1) Homo sapiens The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],