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Cdc25A (phospho Ser75) rabbit pAb
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ES8127
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Cdc25A (phospho Ser75) rabbit pAb
反应性: Human;Mouse;Rat
别名: CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser75. AA range:43-92
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 60kD
基因ID: 993
蛋白序列: P30304
细胞定位: intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,
研究背景: cell division cycle 25A(CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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