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Cyclin E2 (phospho Thr392) rabbit pAb
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ES7964
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Cyclin E2 (phospho Thr392) rabbit pAb
反应性: Human;Mouse
别名: CCNE2; G1/S-specific cyclin-E2
宿主: Rabbit
稀释比: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Cyclin E2 around the phosphorylation site of Thr392. AA range:355-404
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 47kD
基因ID: 9134
蛋白序列: O96020
细胞定位: Nucleus .
研究背景: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008],
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