产品中心

SKI-1 rabbit pAb
一键复制产品信息
ES7865
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
下载说明 ①

Overview

产品名称: SKI-1 rabbit pAb
反应性: Human;Mouse;Rat
别名: MBTPS1; KIAA0091; S1P; SKI1; Membrane-bound transcription factor site-1 protease; Endopeptidase S1P; Subtilisin/kexin-isozyme 1; SKI-1
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原: Synthesized peptide derived from SKI-1 . at AA range: 180-260
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 130kD
基因ID: 8720
蛋白序列: Q14703
细胞定位: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . May sort to other organelles, including lysosomal and/or endosomal compartments. .
研究背景: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014],
关闭

在线咨询

Online consultation

  • 在线咨询
  • 技术支持

关注微信公众号

微信扫一扫立即咨询

微信电脑端咨询

微信扫一扫立即咨询

微信电脑端咨询
关闭