REPS1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1
宿主:
Rabbit
稀释比:
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原:
The antiserum was produced against synthesized peptide derived from human REPS1. AA range:597-646
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
80kD
基因ID:
85021
蛋白序列:
Q96D71
细胞定位:
Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
研究背景:
This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],