THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
宿主:
Rabbit
稀释比:
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
免疫原:
The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
60kD
基因ID:
7056
蛋白序列:
P07204
细胞定位:
Membrane; Single-pass type I membrane protein.
研究背景:
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],