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NIPP1 rabbit pAb
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ES6707
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: NIPP1 rabbit pAb
反应性: Human;Mouse;Rat
别名: PPP1R8; ARD1; NIPP1; Nuclear inhibitor of protein phosphatase 1; NIPP-1; Protein phosphatase 1 regulatory inhibitor subunit 8
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human PPP1R8. AA range:196-245
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 40kD
基因ID: 5511
蛋白序列: Q12972
细胞定位: Nucleus. Nucleus speckle. Primarily, but not exclusively, nuclear.; [Isoform Gamma]: Cytoplasm. Found mainly in the cytoplasm.
研究背景: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008],
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