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FGFR-5 rabbit pAb
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ES6628
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: FGFR-5 rabbit pAb
反应性: Human;Mouse
别名: FGFRL1; FGFR5; FHFR; Fibroblast growth factor receptor-like 1; FGF receptor-like protein 1; FGF homologous factor receptor; FGFR-like protein; Fibroblast growth factor receptor 5; FGFR-5
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: Synthesized peptide derived from FGFR-5 . at AA range: 130-210
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 54kD
基因ID: 53834
蛋白序列: Q8N441
细胞定位: Membrane ; Single-pass type I membrane protein . Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.
研究背景: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other
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