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Pim-1 rabbit pAb
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ES6589
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Pim-1 rabbit pAb
反应性: Human;Mouse;Rat
别名: PIM1; Serine/threonine-protein kinase pim-1
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: The antiserum was produced against synthesized peptide derived from human Pim-1. AA range:281-330
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 50kD
基因ID: 5292
蛋白序列: P11309
细胞定位: [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 2]: Cell membrane.
研究背景: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],
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