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PHKB rabbit pAb
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ES6585
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PHKB rabbit pAb
反应性: Human;Mouse
别名: PHKB; Phosphorylase b kinase regulatory subunit beta; Phosphorylase kinase subunit beta
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: The antiserum was produced against synthesized peptide derived from human KPBB. AA range:661-710
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 124kD
基因ID: 5257
蛋白序列: Q93100
细胞定位: Cell membrane ; Lipid-anchor ; Cytoplasmic side .
研究背景: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency
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