LEF-1 (phospho Ser42) rabbit pAb-ELK科鹿生物-ELISA试剂盒、抗体、蛋白、分子

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LEF-1 (phospho Ser42) rabbit pAb

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ES6501

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

产品名称:	LEF-1 (phospho Ser42) rabbit pAb
反应性:	Human;Mouse;Rat
别名:	LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
宿主:	Rabbit
稀释比:	WB 1:500-2000;IHC-p 1:50-300
免疫原:	The antiserum was produced against synthesized peptide derived from human LEF-1 around the phosphorylation site of Ser42. AA range:8-57
储存条件:	-20°C/1 year
克隆性:	Polyclonal
抗体亚型:	IgG
浓度:	1 mg/ml
实测条带:	55kD
基因ID:	51176
蛋白序列:	Q9UJU2
细胞定位:	Nucleus . Found in nuclear bodies upon PIASG binding. .
研究背景:	This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Western Blot analysis of 293 cells using Phospho-LEF-1 (S42) Polyclonal Antibody
Western blot analysis of lysates from 293 cells treated with paclitaxel 1uM 24h, using LEF-1 (Phospho-Ser42) Antibody. The lane on the right is blocked with the phospho peptide.
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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