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PCB rabbit pAb
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ES6488
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: PCB rabbit pAb
反应性: Human;Mouse;Rat
别名: PC; Pyruvate carboxylase; mitochondrial; Pyruvic carboxylase; PCB
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human PC. AA range:357-406
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 120kD
基因ID: 5091
蛋白序列: P11498
细胞定位: Mitochondrion matrix .
研究背景: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],
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