产品中心

GPR143 rabbit pAb
一键复制产品信息
ES6437
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
下载说明 ①

Overview

产品名称: GPR143 rabbit pAb
反应性: Human;Mouse
别名: GPR143; OA1; G-protein coupled receptor 143; Ocular albinism type 1 protein
宿主: Rabbit
稀释比: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 44kD
基因ID: 4935
蛋白序列: P51810
细胞定位: Melanosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .
研究背景: This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009],
关闭

在线咨询

Online consultation

  • 在线咨询
  • 技术支持

关注微信公众号

微信扫一扫立即咨询

微信电脑端咨询

微信扫一扫立即咨询

微信电脑端咨询
关闭