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Na+/K+-ATPase α2 rabbit pAb
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ES6362
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Na+/K+-ATPase α2 rabbit pAb
反应性: Human;Mouse;Rat;Monkey
别名: ATP1A2; KIAA0778; Sodium/potassium-transporting ATPase subunit alpha-2; Na(+)/K(+) ATPase alpha-2 subunit; Sodium pump subunit alpha-2
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原: The antiserum was produced against synthesized peptide derived from human ATP1A2. AA range:971-1020
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 112kD
基因ID: 477
蛋白序列: P50993
细胞定位: Membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .
研究背景: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008],
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