RPL10A; NEDD6; 60S ribosomal protein L10a; CSA-19; Neural precursor cell expressed developmentally down-regulated protein 6; NEDD-6
宿主:
Rabbit
稀释比:
WB 1:500-2000;IHC-p 1:50-300
免疫原:
Synthesized peptide derived from Ribosomal Protein L10A . at AA range: 30-110
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
25kD
基因ID:
4736
蛋白序列:
P62906
细胞定位:
nucleus,nucleolus,cytoplasm,cytosol,ribosome,focal adhesion,large ribosomal subunit,membrane,cytosolic large ribosomal subunit,extracellular exosome,
研究背景:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes