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Manic Fringe rabbit pAb
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ES6237
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Manic Fringe rabbit pAb
反应性: Human;Mouse;Rat
别名: MFNG; Beta-1; 3-N-acetylglucosaminyltransferase manic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human MFNG. AA range:61-110
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 38kD
基因ID: 4242
蛋白序列: O00587
细胞定位: Golgi apparatus membrane ; Single-pass type II membrane protein .
研究背景: This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],
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