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MEF-2D (phospho Ser444) rabbit pAb
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ES6225
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: MEF-2D (phospho Ser444) rabbit pAb
反应性: Human;Mouse;Rat
别名: MEF2D; Myocyte-specific enhancer factor 2D
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human MEF2D around the phosphorylation site of Ser444. AA range:410-459
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 55kD
基因ID: 4209
蛋白序列: Q14814
细胞定位: Nucleus . Translocated by HDAC4 to nuclear dots.
研究背景: This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
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