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Lck (phospho Tyr192) rabbit pAb
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ES6092
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: Lck (phospho Tyr192) rabbit pAb
反应性: Human;Mouse;Rat
别名: LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Lck around the phosphorylation site of Tyr192. AA range:161-210
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 56kD
基因ID: 3932
蛋白序列: P06239
细胞定位: Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytosol . Present in lipid rafts in an inactive form. .
研究背景: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016],
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