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KIR3.1 rabbit pAb
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ES6005
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: KIR3.1 rabbit pAb
反应性: Human;Mouse;Rat
别名: KCNJ3; GIRK1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K(+) channel Kir3.1; Potassium channel; inwardly rectifying subfamily J member 3
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: The antiserum was produced against synthesized peptide derived from human GIRK1/KIR3.1/KCNJ3. AA range:151-200
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 56kD
基因ID: 3760
蛋白序列: P48549
细胞定位: Membrane; Multi-pass membrane protein.
研究背景: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, at
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