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PDX-1 rabbit pAb
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ES5913
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PDX-1 rabbit pAb
反应性: Human;Mouse;Rat
别名: PDX1; IPF1; Pancreas/duodenum homeobox protein 1; PDX-1; Glucose-sensitive factor; GSF; Insulin promoter factor 1; IPF-1; Insulin upstream factor 1; IUF-1; Islet/duodenum homeobox-1; IDX-1; Somatostatin-transactivating factor 1; STF-1
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: The antiserum was produced against synthesized peptide derived from human PDX1. AA range:27-76
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 42kD
基因ID: 3651
蛋白序列: P52945
细胞定位: Nucleus. Cytoplasm, cytosol .
研究背景: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008],
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