GPS2 rabbit pAb-ELK科鹿生物-ELISA试剂盒、抗体、蛋白、分子

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GPS2 rabbit pAb

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ES5628

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

产品名称:	GPS2 rabbit pAb
反应性:	Human;Mouse;Rat
别名:	GPS2; G protein pathway suppressor 2; GPS-2
宿主:	Rabbit
稀释比:	Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原:	The antiserum was produced against synthesized peptide derived from human GPS2. AA range:11-60
储存条件:	-20°C/1 year
克隆性:	Polyclonal
抗体亚型:	IgG
浓度:	1 mg/ml
实测条带:	40kD
基因ID:	2874
蛋白序列:	Q13227
细胞定位:	Nucleus . Mitochondrion . Cytoplasm, cytosol . Sumoylation regulates the subcellular location (PubMed:24943844). Relocates from the mitochondria to the nucleus following desumoylation, leading to mediate mitochondrial stress response (By similarity). .
研究背景:	This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008],

Western Blot analysis of RAW264.7 cells using GPS2 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western blot analysis of lysates from RAW264.7 cells, using GPS2 Antibody. The lane on the right is blocked with the synthesized peptide.

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