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Ksr2 rabbit pAb
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ES5584
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: Ksr2 rabbit pAb
反应性: Human;Mouse
别名: KSR2; Kinase suppressor of Ras 2; hKSR2
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 108kD
基因ID: 283455
蛋白序列: Q6VAB6
细胞定位: Cytoplasm . Membrane ; Peripheral membrane protein .
研究背景: domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.,PTM:Phosphorylated on Ser-474 by MARK3.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.,tissue specificity:Mainly expressed in brain and kidney.,
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