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Cadherin-20 rabbit pAb
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ES5578
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: Cadherin-20 rabbit pAb
反应性: Human;Mouse;Rat
别名: CDH20; CDH7L3; Cadherin-20
宿主: Rabbit
稀释比: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 89kD
基因ID: 28316
蛋白序列: Q9HBT6
细胞定位: Cell membrane; Single-pass type I membrane protein.
研究背景: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],
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