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Dynein IC1 rabbit pAb
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ES5529
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Dynein IC1 rabbit pAb
反应性: Human;Mouse;Rat
别名: DNAI1; Dynein intermediate chain 1; axonemal; Axonemal dynein intermediate chain 1
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human DNAI1. AA range:211-260
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 79kD
基因ID: 27019
蛋白序列: Q9UI46
细胞定位: Dynein axonemal particle . Cytoplasm, cytoskeleton, cilium axoneme .
研究背景: This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
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