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NARF rabbit pAb
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ES5498
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: NARF rabbit pAb
反应性: Human;Rat;Mouse;
别名: NARF; Nuclear prelamin A recognition factor; Iron-only hydrogenase-like protein 2; IOP2
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原: The antiserum was produced against synthesized peptide derived from human NARF. AA range:262-311
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 51kD
基因ID: 26502
蛋白序列: Q9UHQ1
细胞定位: Nucleus .
研究背景: Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It
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