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GCKR rabbit pAb
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ES5494
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: GCKR rabbit pAb
反应性: Human;Mouse;Rat
别名: GCKR; Glucokinase regulatory protein; Glucokinase regulator
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 68kD
基因ID: 2646
蛋白序列: Q14397
细胞定位: Cytoplasm . Nucleus . Mitochondrion . Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus. .
研究背景: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008],
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