产品中心

IL-17Rα rabbit pAb
一键复制产品信息
ES5381
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
下载说明 ①

Overview

产品名称: IL-17Rα rabbit pAb
反应性: Human;Mouse
别名: IL17RA; IL17R; Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized peptide derived from human IL17RA. AA range:141-190
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 90kD
基因ID: 23765
蛋白序列: Q96F46
细胞定位: [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
研究背景: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],
关闭

在线咨询

Online consultation

  • 在线咨询
  • 技术支持

关注微信公众号

微信扫一扫立即咨询

微信电脑端咨询

微信扫一扫立即咨询

微信电脑端咨询
关闭