The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
173kD
基因ID:
23365
蛋白序列:
Q9NZN5
细胞定位:
Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .
研究背景:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],