RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11
宿主:
Rabbit
稀释比:
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
免疫原:
The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
58kD
基因ID:
22841
蛋白序列:
Q7L804
细胞定位:
Cell projection, phagocytic cup . Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.
研究背景:
function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.,